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Groundbreaking for the Centre for Individualised Infection Medicine (CiiM)

"The COVID-19 pandemic has just shown us how important infection research and personalised medicine are - and that research findings need to to be transferred more quickly from bench to bedside," said Lower Saxony's Science Minister Falko Mohrs. “The life sciences are…

23.11.2022
Persons

Dr Jennifer Debarry

Head of Office
CiiM
Research Group

Clinical Bioinformatics

Personalized medicine offers a significant opportunity to enhance public health by accounting for individual variability in genes, environment, and lifestyle. The "Clinical Bioinformatics" research group follows this direction, aiming to unravel the intricate molecular mechanisms underlying infection and aging. Through this pursuit, we strive to develop precise, individualized treatment strategies. Our research aims to develop and apply "bioinformatics approaches" to pinpoint the genetic and epigenetic factors influencing infection-induced immune responses by integrating multi-omics data from patients and constructing computational models that predict an individual’s risk of infectious diseases. We interact with experimental collaborators and clinical experts to verify our findings and promote their translation into medical treatments or diagnostic procedures. Our ultimate goal is to contribute to the main research focus of CiiM/MHH: the tailored and improved prevention, diagnosis, and treatment of infectious diseases and cancer for individual patients or patient groups. Within this framework, the team led by Prof. Dr. Cheng-Jian Xu is primarily dedicated to the domains of diagnosis, risk assessment, early detection, and patient stratification.

Research Group

Computational Biology for Individualised Medicine

Infections are among the biggest threats to health and the most significant causes of death worldwide. Our aim is to reveal the host genetic risk factors and their downstream molecular pathways, which are crucial to make progress in understanding and treating infectious diseases in an individualised manner as well as to improve the identification of patients at risk. The department of the HZI is part of the developing CiiM and currently housed at the TWINCORE in Hannover. Our group currently has 6 PhD students and 5 postdocs. Students and postdocs – We are always looking for bright and enthusiastic students and postdocs (funded by e.g. the ERC starting grant). For more about our projects, please contact us by email.

Persons

Melanie Rodenberg

Assistent Project management
Local Coordination Units (LCU) of the Network of University Medicine (NUM)
CiiM
Persons

Patrick Kaufhold

Assistent Project management
Local Coordination Units (LCU) of the Network of University Medicine (NUM)
CiiM
Persons

Dr Tetyana Yevsa

Research Group Leader
Local Coordination Units (LCU) of the Network of University Medicine (NUM)
CiiM
Persons

Prof Dr Dr Luka Cicin-Sain

Department head
Individualised Medicine for Viral Infections
HZI Campus
Persons

Prof Dr Cheng-Jian Xu

Research Group Leader
Clinical Bioinformatics
CiiM
Persons

Beate Junk

Technical assistant
Computational Biology for Infection Research
BRICS