Forschung

Neue Forschungsergebnisse aus dem CiiM

Im folgenden finden Sie Publikationen mit CiiM-Beteiligung (Stand März 2020):

2020

Cornberg M., Lok A.S., Terrault N.A., Zoulim F. (2020)
Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference
J.Hepatol., 72 (3)

Licht M.K., Nuss A.M., Volk M., Konzer A., Beckstette M., ... , Berghoff B.A., Klug G. (2020)
Adaptation to Photooxidative Stress: Common and Special Strategies of the Alphaproteobacteria Rhodobacter sphaeroides and Rhodobacter capsulatus
Microorganisms., 8 (2)

Alfonso J.C.L., Papaxenopoulou L.A., Mascheroni P., Meyer-Hermann M., Hatzikirou H. (2020)
On the Immunological Consequences of Conventionally Fractionated Radiotherapy
iScience, 23 (3)

Niehaus C.E., Strunz B., Cornillet M., Falk C.S., Schnieders A., Maasoumy B., Hardtke S., Manns M.P., Kraft A.R.M., ... , Björkström N.K., Cornberg M. (2020)
MAIT cells are enriched and highly functional in ascites of patients with decompensated liver cirrhosis
Hepatology, 72 (4)

Zorro M.M., Aguirre-Gamboa R., Mayassi T., Ciszewski C., Barisani D., Hu S., Weersma R.K., Withoff S., Li Y., Wijmenga C., ... , Jabri B., Jonkers I.H. (2020)
Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes
J.Autoimmun., 108 (March)

Qi C., Jiang Y., Yang I.V., Forno E., Wang T., Vonk J.M., Gehring U., Smit H.A., Milanzi E.B., Carpaij O.A., Berg M., Hesse L., Brouwer S., Cardwell J., Vermeulen C.J., costa-Perez E., Canino G., Boutaoui N., van den Berge M., Teichmann S.A., Nawijn M.C., Chen W., Celedon J.C., ... , Xu C.J., Koppelman G.H. (2020)
Nasal DNA methylation profiling of asthma and rhinitis
J.Allergy Clin.Immunol., 145 (6)

de Araujo L.S., Pessler K., Suhs K.W., Novoselova N., Klawonn F., Kuhn M., Kaever V., Muller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2020)
Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis
J.Transl.Med., 18 (1)

Montaseri G., Alfonso J.C.L., Hatzikirou H., Meyer-Hermann M. (2020)
A minimal modeling framework of radiation and immune system synergy to assist radiotherapy planning
J.Theor.Biol., 486 (February)

Vermeulen C.J., Xu C.J., Vonk J.M., Ten Hacken N.H.T., Timens W., Heijink I.H., Nawijn M.C., Boekhoudt J., van Oosterhout A.J., Affleck K., Weckmann M., ... , Koppelman G.H., van den Berge M. (2020)
Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission
Eur.Respir.J., 55 (2)

Rinker F., Bremer C.M., Schröder K., Wiegand S.B., Bremer B., Manns M.P., Kraft A.R., Wedemeyer H., Yang L., Pavlovic V., Wat C., Gerlich W.H., ... , Glebe D., Cornberg M. (2020)
Quantitation of large, middle and small hepatitis B surface proteins in HBeAg-positive patients treated with peginterferon alfa-2a
Liver Int., 40 (2)

Samir M., Vidal R.O., Abdallah F., Capece V., Seehusen F., Geffers R., Hussein A., Ali A.A.H., ... , Bonn S., Pessler F. (2020)
Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1)
RNA.Biol., 17 (1)

2019

Cornberg M., Lok A.S., Terrault N.A., Zoulim F. (2020)
Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference
J.Hepatol., 72 (3)

de Araujo L.S., Ribeiro-Alves M., Leal-Calvo T., Leung J., Duran V., Samir M., Talbot S., Tallam A., Mello F.C.Q., Geffers R., ... , Saad M.H.F., Pessler F. (2019)
Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
MBio., 10 (6)

Arshad H., Alfonso J.C.L., Franke R., Michaelis K., Araujo L., Habib A., Zboromyrska Y., Lucke E., Strungaru E., Akmatov M.K., Hatzikirou H., Meyer-Hermann M., Petersmann A., Nauck M., Brönstrup M., Bilitewski U., Abel L., Sievers J., Vila J., Illig T., ... , Schreiber J., Pessler F. (2019)
Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia
J.Transl.Med., 17 (1)

Vermeulen C.J., Xu C.J., Vonk J.M., Ten Hacken N.H.T., Timens W., Heijink I.H., Nawijn M.C., Boekhoudt J., van Oosterhout A.J., Affleck K., Weckmann M., ... , Koppelman G.H., van den Berge M. (2020)
Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission
Eur.Respir.J., 55 (2)

Rinker F., Bremer C.M., Schröder K., Wiegand S.B., Bremer B., Manns M.P., Kraft A.R., Wedemeyer H., Yang L., Pavlovic V., Wat C., Gerlich W.H., ... , Glebe D., Cornberg M. (2020)
Quantitation of large, middle and small hepatitis B surface proteins in HBeAg-positive patients treated with peginterferon alfa-2a
Liver Int., 40 (2)

Qi C., Xu C.J., Koppelman G.H. (2019)
The role of epigenetics in the development of childhood asthma
Expert.Rev.Clin.Immunol., 15 (12)

Meyer-Hermann M. (2019)
Injection of Antibodies against Immunodominant Epitopes Tunes Germinal Centers to Generate Broadly Neutralizing Antibodies
Cell Reports, 29 (5)

Ynga-Durand M.A., Dekhtiarenko I., Cicin-Sain L. (2019)
Vaccine Vectors Harnessing the Power of Cytomegaloviruses
Vaccines.(Basel), 7 (4)

Wiegand S.B., Beggel B., Wranke A., Aliabadi E., Jaroszewicz J., Xu C.J., Li Y., Manns M.P., Lengauer T., Wedemeyer H., Kraft A.R.M., ... , Falk C.S., Cornberg M. (2019)
Soluble immune markers in the different phases of chronic hepatitis B virus infection
Sci Rep, 9 (1)

Samir M., Vidal R.O., Abdallah F., Capece V., Seehusen F., Geffers R., Hussein A., Ali A.A.H., ... , Bonn S., Pessler F. (2020)
Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1)
RNA.Biol., 17 (1)

Chen F., Lukat P., Iqbal A.A., Saile K., Kaever V., van den Heuvel J., Blankenfeldt W., ... , Büssow K., Pessler F. (2019)
Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
Proc.Natl.Acad.Sci.U.S.A, 116 (41)

Arulraj T., Binder S.C., Robert P.A., Meyer-Hermann M. (2019)
Synchronous germinal center onset impacts the efficiency of antibody responses
Front.Immunol., 10

Sharma-Chawla N., Stegemann-Koniszewski S., Christen H., Boehme J.D., Kershaw O., Schreiber J., Guzmán C.A., ... , Bruder D., Hernandez-Vargas E.A. (2019)
In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection
Front Immunol., 10

Akmatov M.K., Riese P., Trittel S., May M., Prokein J., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2019)
Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly
BMC Infect.Dis., 19 (1)

Mascheroni P., Lopez Alfonso J.C., Kalli M., Stylianopoulos T., Meyer-Hermann M., Hatzikirou H. (2019)
On the Impact of Chemo-Mechanically Induced Phenotypic Transitions in Gliomas
Cancers.(Basel), 11 (5)

Schlicker L., Boers H.M., Dudek C.A., Zhao G., Barua A., Trezzi J.P., Meyer-Hermann M., ... , Jacobs D.M., Hiller K. (2019)
Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans
Metabolites., 9 (5)

Cicin-Sain L. (2019)
Cytomegalovirus memory inflation and immune protection
Med.Microbiol Immunol, 208 (3-4)

Sühs K.W., Novoselova N., Kuhn M., Seegers L., Kaever V., Müller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2019)
Kynurenine is a cerebrospinal fluid biomarker for bacterial and viral CNS infections
J.Infect.Dis., 220 (1)

Ratuszny D., Sühs K.W., Novoselova N., Kuhn M., Kaever V., Skripuletz T., ... , Pessler F., Stangel M. (2019)
Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis
Int J Mol Sci, 20 (2)